USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: S10A6_HUMAN USC-OGP 2-DE database:  S10A6_HUMAN S10A6_HUMAN General information about the entry View entry in simple text format Entry name S10A6_HUMAN Primary accession number P06703 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Protein S100-A6; AltName: Full=Calcyclin; AltName: Full=Growth factor-inducible protein 2A9; AltName: Full=MLN 4; AltName: Full=Prolactin receptor-associated protein; Short=PRA; AltName: Full=S100 calcium-binding protein A6;. Gene name Name=S100A6 Synonyms=CACY Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1359: pI=5.15; Mw=12450 SPOT OGP-1360: pI=5.19; Mw=12337 Cross-references UniProtKB/Swiss-Prot P06703; S10A6_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name S10A6_HUMAN Primary accession number P06703 Secondary accession number(s) D3DV39 Q5RHS4 Sequence was last modified on  January 1, 1988 (version 1) Annotations were last modified on  March 15, 2017 (version 176) Name and origin of the protein Description RecName: Full=Protein S100-A6; AltName: Full=Calcyclin; AltName: Full=Growth factor-inducible protein 2A9; AltName: Full=MLN 4; AltName: Full=Prolactin receptor-associated protein; Short=PRA; AltName: Full=S100 calcium-binding protein A6; Gene name Name=S100A6 Synonyms=CACY Encoded on Name=S100A6; Synonyms=CACY Keywords 3D-structure; Acetylation; Calcium; Cell membrane; Complete proteome; Cytoplasm; Direct protein sequencing; Membrane; Metal-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M14300; AAA35886.1; -; mRNA EMBL J02763; AAA51905.1; -; Genomic_DNA EMBL M18981; AAA51906.1; -; mRNA EMBL AY034480; AAK59702.1; -; Genomic_DNA EMBL BT006965; AAP35611.1; -; mRNA EMBL BX470102; CAI14752.1; -; Genomic_DNA EMBL CH471121; EAW53318.1; -; Genomic_DNA EMBL CH471121; EAW53320.1; -; Genomic_DNA EMBL CH471121; EAW53321.1; -; Genomic_DNA EMBL CH471121; EAW53322.1; -; Genomic_DNA EMBL CH471121; EAW53323.1; -; Genomic_DNA EMBL CH471121; EAW53324.1; -; Genomic_DNA EMBL CH471121; EAW53325.1; -; Genomic_DNA EMBL CH471121; EAW53326.1; -; Genomic_DNA EMBL BC001431; AAH01431.1; -; mRNA EMBL BC009017; AAH09017.1; -; mRNA CCDS CCDS1040.1; -; . PIR A28363; BCHUY; . RefSeq NP_055439.1; NM_014624.3; . RefSeq XP_016857522.1; XM_017002033.1; . UniGene Hs.275243; -; . PDB 1K8U; X-ray; 1.15 A; A=1-90 PDB 1K96; X-ray; 1.44 A; A=1-90 PDB 1K9K; X-ray; 1.76 A; A/B=1-90 PDB 1K9P; X-ray; 1.90 A; A=1-90 PDB 2M1K; NMR; -; B/D=1-90 PDB 4YBH; X-ray; 2.40 A; B=1-90 PDBsum 1K8U; -; . PDBsum 1K96; -; . PDBsum 1K9K; -; . PDBsum 1K9P; -; . PDBsum 2M1K; -; . PDBsum 4YBH; -; . ProteinModelPortal P06703; -; . SMR P06703; -; . BioGrid 112185; 29; . IntAct P06703; 18; . MINT MINT-3005220; -; . STRING 9606.ENSP00000357708; -; . iPTMnet P06703; -; . PhosphoSitePlus P06703; -; . SwissPalm P06703; -; . BioMuta S100A6; -; . DMDM 116509; -; . DOSAC-COBS-2DPAGE P06703; -; . EPD P06703; -; . MaxQB P06703; -; . PaxDb P06703; -; . PeptideAtlas P06703; -; . PRIDE P06703; -; . TopDownProteomics P06703; -; . DNASU 6277; -; . Ensembl ENST00000368719; ENSP00000357708; ENSG00000197956; . Ensembl ENST00000368720; ENSP00000357709; ENSG00000197956; . Ensembl ENST00000496817; ENSP00000473589; ENSG00000197956; . GeneID 6277; -; . KEGG hsa:6277; -; . UCSC uc001fbw.2; human; . CTD 6277; -; . DisGeNET 6277; -; . GeneCards S100A6; -; . HGNC HGNC:10496; S100A6; . HPA CAB002601; -; . HPA CAB040549; -; . HPA HPA007575; -; . MIM 114110; gene; . neXtProt NX_P06703; -; . OpenTargets ENSG00000197956; -; . PharmGKB PA34908; -; . eggNOG ENOG410IYT5; Eukaryota; . eggNOG ENOG410Z6I6; LUCA; . GeneTree ENSGT00760000119034; -; . HOGENOM HOG000246968; -; . HOVERGEN HBG001479; -; . InParanoid P06703; -; . OMA QVVNFQE; -; . OrthoDB EOG091G10JX; -; . PhylomeDB P06703; -; . TreeFam TF332727; -; . ChiTaRS S100A6; human; . EvolutionaryTrace P06703; -; . GeneWiki S100A6; -; . GenomeRNAi 6277; -; . PRO PR:P06703; -; . Proteomes UP000005640; Chromosome 1; . Bgee ENSG00000197956; -; . CleanEx HS_S100A6; -; . ExpressionAtlas P06703; baseline and differential; . Genevisible P06703; HS; . GO GO:0005737; C:cytoplasm; IDA:UniProtKB; . GO GO:0005829; C:cytosol; IDA:UniProtKB; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0031234; C:extrinsic component of cytoplasmic side of plasma membrane; IDA:UniProtKB; . GO GO:0005635; C:nuclear envelope; IDA:UniProtKB; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB; . GO GO:0001726; C:ruffle; IDA:UniProtKB; . GO GO:0005509; F:calcium ion binding; IDA:UniProtKB; . GO GO:0048306; F:calcium-dependent protein binding; IDA:UniProtKB; . GO GO:0015075; F:ion transmembrane transporter activity; IEA:Ensembl; . GO GO:0042803; F:protein homodimerization activity; IDA:UniProtKB; . GO GO:0044548; F:S100 protein binding; IPI:UniProtKB; . GO GO:0005523; F:tropomyosin binding; IDA:UniProtKB; . GO GO:0008270; F:zinc ion binding; IEA:Ensembl; . GO GO:0007409; P:axonogenesis; NAS:UniProtKB; . GO GO:0048146; P:positive regulation of fibroblast proliferation; NAS:UniProtKB; . GO GO:0007165; P:signal transduction; TAS:UniProtKB; . CDD cd05029; S-100A6; 1; . Gene3D 1.10.238.10; -; 1; . InterPro IPR011992; EF-hand-dom_pair; . InterPro IPR018247; EF_Hand_1_Ca_BS; . InterPro IPR002048; EF_hand_dom; . InterPro IPR034118; S-100A6; . InterPro IPR001751; S100/CaBP-9k_CS; . InterPro IPR013787; S100_Ca-bd_sub; . Pfam PF01023; S_100; 1; . SMART SM00054; EFh; 1; . SMART SM01394; S_100; 1; . SUPFAM SSF47473; SSF47473; 1; . PROSITE PS00018; EF_HAND_1; 1; . PROSITE PS50222; EF_HAND_2; 1; . PROSITE PS00303; S100_CABP; 1; .

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• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
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• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
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